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Primary intestinal lymphangiectasia diagnosed by capsule endoscopy and double balloon enteros

Authors
 Tak Geun Oh ; Joo Won Chung ; Si Young Song ; Jung Yeob Park ; Jin Sung Lee ; Seok-Joo Han ; Hee Man Kim 
Citation
 World Journal of Gastrointestinal Endoscopy, Vol.3(11) : 235~240, 2011 
Journal Title
 World Journal of Gastrointestinal Endoscopy 
ISSN
 1948-5190 
Issue Date
2011
Abstract
Primary intestinal lymphangiectasia (PIL) is a rare disorder characterized by dilated intestinal lymphatics and the development of protein-losing enteropathy. Patients with PIL develop hypoalbuminemia, hypocalcemia, lymphopenia and hypogammaglobulinemia, and present with bilateral lower limb edema, fatigue, abdominal pain and diarrhea. Endoscopy reveals diffusely elongated, circumferential and polypoid mucosae covered with whitish enlarged villi, all of which indicate intestinal lymphangiectasia. Diagnosis is confirmed by characteristic tissue pathology, which includes dilated intestinal lymphatics with diffusely swollen mucosa and enlarged villi. The prevalence of PIL has increased since the introduction of capsule endoscopy. The etiology and prevalence of PIL remain unknown. Some studies have reported that several genes and regulatory molecules for lymphangiogenesis are related to PIL. We report the case of a patient with PIL involving the entire small bowel that was confirmed by capsule endoscopy and double-balloon enteroscopy-guided tissue pathology who carried a deletion on chromosome 4q25. The relationship between this deletion on chromosome 4 and PIL remains to be investigated.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94683
DOI
10.4253/wjge.v3.i11.235
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Surgery
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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