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단일염기다형성을 이용한 치과 질환 유전체 연구

Other Titles
 Genetic association study of single nucleotide polymorphism in dentistry 
Authors
 김지환 ; 이재훈 
Citation
 Journal of Korean Academy of Prosthodontics (대한치과보철학회지), Vol.49(4) : 341~345, 2011 
Journal Title
 Journal of Korean Academy of Prosthodontics (대한치과보철학회지) 
ISSN
 3012-2875 
Issue Date
2011
Abstract
Genetic association study has been progressed in medicine along with advance in genetic technology. It focused on the individual differences in genotype due to errors occurring during DNA duplication, which can cause vulnerability to specific diseases. Polymorphism defines the varieties in phenotype due to those genetic variations. Polymorphism due to change in one DNA base sequence is called as a Single Nucleotide Polymorphism. In the near future, the evaluation of relative risk to specific disease according to SNP will be essential part of fundamental of medicine for the diagnosis, treatment and prevention. Dental caries and periodontal diseases has been first subject to genetic association study in dentistry and broaden out to other areas like bone formation and resorption. This article presents the current state of genetic association study and its application to dentistry
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94602
DOI
10.4047/jkap.2011.49.4.341
Appears in Collections:
1. 연구논문 > 2. College of Dentistry > Dept. of Prosthodontics
Yonsei Authors
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