Cited 0 times in

Evaluation of a fully automated treponemal test and comparison with conventional VDRL and FTA-ABS tests.

Title
 Evaluation of a fully automated treponemal test and comparison with conventional VDRL and FTA-ABS tests. 
Authors
 Yongjung Park ; Younhee Park ; Hyon-Suk Kim ; Myoung Hee Park ; Shin Young Joo 
Issue Date
2011
Journal Title
 American Journal of Clinical Pathology 
ISSN
 0002-9173 
Citation
 American Journal of Clinical Pathology, Vol.136(5) : 705~710, 2011 
Abstract
We evaluated analytic performances of an automated treponemal test and compared this test with the Venereal Disease Research Laboratory test (VDRL) and fluorescent treponemal antibody absorption test (FTA-ABS). Precision performance of the Architect Syphilis TP assay (TP; Abbott Japan, Tokyo, Japan) was assessed, and 150 serum samples were assayed with the TP before and after heat inactivation to estimate the effect of heat inactivation. A total of 616 specimens were tested with the FTA-ABS and TP, and 400 were examined with the VDRL. The TP showed good precision performance with total imprecision of less than a 10% coefficient of variation. An excellent linear relationship between results before and after heat inactivation was observed (R(2) = 0.9961). The FTA-ABS and TP agreed well with a κ coefficient of 0.981. The concordance rate between the FTA-ABS and TP was the highest (99.0%), followed by the rates between FTA-ABS and VDRL (85.0%) and between TP and VDRL (83.8%). The automated TP assay may be adequate for screening for syphilis in a large volume of samples and can be an alternative to FTA-ABS.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94556
DOI
10.1309/AJCP0WOK0QDYGDCM
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Laboratory Medicine
Yonsei Authors
사서에게 알리기
  feedback
Files in This Item:
T201103922.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse