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한국 아동 집단의 구조 뇌연결지도

 한국 아동 집단의 구조 뇌연결지도
Other Titles
 Anatomical Brain Connectivity Map of Korean Children
 엄민희; 박범희; 박해정
Issue Date
Journal Title
 Journal of the Korean Society of Magnetic Resonance in Medicine (대한자기공명의과학회지)
 Journal of the Korean Society of Magnetic Resonance in Medicine (대한자기공명의과학회지), Vol.15(2) : 110~122, 2011
PURPOSE: The purpose of this study is to establish the method generating human brain anatomical connectivity from Korean children and evaluating the network topological properties using small-world network analysis. MATERIALS AND METHODS: Using diffusion tensor images (DTI) and parcellation maps of structural MRIs acquired from twelve healthy Korean children, we generated a brain structural connectivity matrix for individual. We applied one sample t-test to the connectivity maps to derive a representative anatomical connectivity for the group. By spatially normalizing the white matter bundles of participants into a template standard space, we obtained the anatomical brain network model. Network properties including clustering coefficient, characteristic path length, and global/local efficiency were also calculated. RESULTS: We found that the structural connectivity of Korean children group preserves the small-world properties. The anatomical connectivity map obtained in this study showed that children group had higher intra-hemispheric connectivity than inter-hemispheric connectivity. We also observed that the neural connectivity of the group is high between brain stem and motorsensory areas. CONCLUSION: We suggested a method to examine the anatomical brain network of Korean children group. The proposed method can be used to evaluate the efficiency of anatomical brain networks in people with disease
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1. 연구논문 > 1. College of Medicine > Dept. of Nuclear Medicine
Yonsei Authors
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