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Optimal sedative dose of propofol to start MRI in children with cerebral palsy.

Title
 Optimal sedative dose of propofol to start MRI in children with cerebral palsy. 
Authors
 Eun Jung Kim ; Youn Yi Jo ; Hae Keum Kil 
Issue Date
2011
Journal Title
 Korean Journal of Anesthesiology 
ISSN
 2005-6419 
Citation
 Korean Journal of Anesthesiology, Vol.61(3) : 216~219, 2011 
Abstract
BACKGROUND: This study was designed to determine the optimal sedative dose of propofol to start brain magnetic resonance imaging (MRI) in children with cerebral palsy (CP). METHODS: Twenty children, aged 0.5-5 years, were administered propofol to achieve a University of Michigan Sedation Scale (UMSS) score ≥ 3 in the MRI room. The proper dose of propofol was determined using the up-and-down method. RESULTS: The ED50 and ED95 for successful sedation with a UMSS ≥ 3 were 2.07 mg/kg (95% CI 1.69-2.56) and 2.69 mg/kg (95% CI 2.35-5.59). Respiratory events occurred in 5 patients and were resolved with neck extension, chin lift, or transient respiratory assistance with successful sedation. CONCLUSIONS: Low dose propofol can safely facilitate the initiation of MRI in children with CP
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94389
DOI
10.4097/Clinical Research Article kjae.2011.61.3.216
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Anesthesiology and Pain Medicine
Yonsei Authors
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