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Chlamydia trachomatis 검출을 위한 실시간 중합효소연쇄반응법 2종의 평가

Title
 Chlamydia trachomatis 검출을 위한 실시간 중합효소연쇄반응법 2종의 평가
Other Titles
 Evaluation of two real-time PCR assays for the detection of Chlamydia trachomatis
Authors
 이은영; 김신영; 김현숙
Issue Date
2011
Journal Title
 Journal of Laboratory Medicine and Quality Assurance (임상검사와 정도관리)
ISSN
 1225-097X
Citation
 Journal of Laboratory Medicine and Quality Assurance (임상검사와 정도관리), Vol.33(1) : 43~47, 2011
Abstract
BackgroundChlamydia trachomatis is common etiological agent of sexual transmitted disease. We evaluated two real-time PCR assays for the detection of C. trachomatis; Cobas TaqMan CT test v2.0 (Roche Diagnostics, Switzerland) and AdvanSure CT/NG real-time PCR (LG Life Sciences, Korea). And we compared performance of two real-time PCR assays with Cobas Amplicor CT test (Roche Diagnostics, Switzerland).Methods:Seventy-nine cervical swab specimens collected from patients with suspected C. trachomatis infection were tested using CTM CT, ADVANSURE, and AMPLICOR for the detection of C. trachomatis. Results:Twenty-five (31.6%) samples showed positive results in all three assays. The positive and negative concordance rates among three assays were 100% Conclusion:CTM CT and ADVANSURE showed excellent agreement with AMPLICOR. Therefore, these assays were reliable for the evaluation of C. trachomatis infection.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94263
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Laboratory Medicine
Yonsei Authors
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