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Influence of blue light-filtering intraocular lenses on retinal nerve fiber layer measurements by spectral-domain optical coherence tomography.

Authors
 Ji Hyun Kim  ;  Na Rae Kim  ;  Eun Suk Lee  ;  Seungsoo Rho  ;  Sung Yong Kang  ;  Chan Yun Kim 
Citation
 CURRENT EYE RESEARCH, Vol.36(10) : 937-942, 2011 
Journal Title
CURRENT EYE RESEARCH
ISSN
 0271-3683 
Issue Date
2011
MeSH
Humans ; Lens Implantation,Intraocular* ; Lenses,Intraocular* ; NerveFibers/pathology* ; Phacoemulsification* ; Prospective Studies ; Prosthesis Design ; Pseudophakia/physiopathology ; RetinalGanglion Cells/pathology* ; Tomography,OpticalCoherence ; Visual Acuity
Keywords
Blue-light filtering intraocular lens ; Optical coherence tomography ; Retinal nerve fiber layer thickness ; Spectral-domain ; Signal strength
Abstract
PURPOSE: The purpose of this study was to assess the influence of blue light-filtering intraocular lenses (IOL) on peripapillary retinal nerve fiber layer (RNFL) thickness measurements by spectral-domain (SD) optical coherence tomography (OCT).

METHODS: This prospective study included 50 eyes of 50 patients. Patients were randomly assigned to receive either a blue light-filtering IOL (acrysof IQ (SN60WF) [Alcon]) or a clear IOL (Tecnis (Z9003) [AMO]). The peripapillary RNFL thickness was measured using a Cirrus SD OCT before and 8 weeks after cataract surgery. Perioperative differences in RNFL thickness measurements and signal strengths (SS) were evaluated and compared in both IOL groups.

RESULTS: Thirty-nine eyes of 39 patients were included in the final analysis. There was a significant increase in average RNFL thickness and SS after cataract surgery in both IOL groups. No significant difference in perioperative changes of RNFL measurements was noted between yellow and clear IOL groups. In the multivariable analysis, the factor affecting perioperative differences of RNFL measurements was not IOL type but SS.

CONCLUSIONS: Our data suggests that blue-light filtering IOL does not influence RNFL thickness measurements by Cirrus SD-OCT.
Full Text
http://informahealthcare.com/doi/abs/10.3109/02713683.2011.597535
DOI
10.3109/02713683.2011.597535
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Na Rae(김나래)
Kim, Ji Hyun(김지현)
Kim, Chan Yun(김찬윤) ORCID logo https://orcid.org/0000-0002-8373-9999
Rho, Seung Soo(노승수)
Lee, Eun Suk(이은석)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94156
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