The effects of serotonin transporter promoter and monoamine oxidase A gene polymorphisms on trait emotional intelligence
Kim S.J. ; Kang J.I. ; Song D.-H. ; Namkoong K.
Neuropsychobiology, Vol.64(4) : 224~230, 2011
OBJECTIVE: The purpose of this study was to evaluate the influences of major serotonin-related genetic variants of the serotonin transporter-linked promoter region (5-HTTLPR), tryptophan hydroxylase 1 gene (TPH1) and monoamine oxidase A gene (MAOA-EcoRV) on trait emotional intelligence (EI).
METHODS: The Trait Meta-Mood Scale (TMMS) measuring trait EI and genotyping were performed in 336 healthy Korean college students (204 males, 132 females).
RESULTS: Among the male participants, those with the T genotype of MAOA (lower MAOA activity) had significantly lower subscale scores on the TMMS than those with the C genotype (higher MAOA activity) did. Additionally, male participants with the s/s genotype of the 5-HTTLPR gene had significantly lower attention subscale scores and total TMMS scores than those with the non-s/s (l/l + l/s) genotypes did. Among the female participants, there were no associations between any of the 5-HTTLPR, TPH1 or MAOA-EcoRV polymorphisms and any of the TMMS scores.
CONCLUSION: These findings suggest a potential genetic basis of EI with regard to attention to one's own feelings involving the serotonin system in males.