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이식신사구체병증의 병인

Title
이식신사구체병증의 병인
Other Titles
Pathogenesis of Transplant Glomerulopathy
Authors
임범진;정현주
Issue Date
2011
Journal Title
Journal of the Korean Society for Transplantation(대한이식학회지)
ISSN
1598-1711
Citation
Journal of the Korean Society for Transplantation(대한이식학회지), Vol.25(2) : 71~75, 2011
Abstract
Transplant glomerulopathy is a late complication of renal transplantation. The characteristic morphology of transplant glomerulopathy includes thickening of glomerular capillary loops with double contour, and duplication of glomerular basement membrane on electron microscopy. Clinical and experimental evidences support the role of antibody-mediated immune mechanism in the development of transplant glomerulopathy. Antibody-induced endothelial cell injury is the key pathogenesis of transplant glomerulopathy. The evolution of transplant glomerulopathy in the context of immunologic injury is briefly reviewed.
URI

http://ir.ymlib.yonsei.ac.kr/handle/22282913/93844
DOI
10.4285/jkstn.2011.25.2.71
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Pathology
Yonsei Authors
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