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뇌자기자극을 이용한 운동신경계의 신경생리학적 평가

Title
뇌자기자극을 이용한 운동신경계의 신경생리학적 평가
Other Titles
Neurophysiological Evaluation of the Motor System Using Transcranial Magnetic Stimulation
Authors
신혜원;손영호
Issue Date
2011
Journal Title
Journal of the Korean Society for Clinical Neurophysiology (대한임상신경생리학회)
ISSN
1229-6414
Citation
Journal of the Korean Society for Clinical Neurophysiology (대한임상신경생리학회), Vol.13(1) : 1~12, 2011
Abstract
Transcranial magnetic stimulation (TMS) is a non-invasive tool used to study aspects of human brain physiology, including motor function and the pathophysiology of various brain disorders. A brief electric current passed through a magnetic coil produces a high-intensity magnetic field, which can excite or inhibit the cerebral cortex. Although various brain regions can be evaluated by TMS, most studies have focused on the motor cortex where motor evoked potentials (MEPs) are produced. Single-pulse and paired-pulse TMS can be used to measure the excitability of the motor cortex via various parameters, while repetitive TMS induces cortical plasticity via long-term potentiation or long-term depression-like mechanisms. Therefore, TMS is useful in the evaluation of physiological mechanisms of various neurological diseases, including movement disorders and epilepsy. In addition, it has diagnostic utility in spinal cord diseases, amyotrophic lateral sclerosis and demyelinating diseases. The therapeutic effects of repetitive TMS on stroke, Parkinson disease and focal hand dystonia are limited since the duration and clinical benefits seem to be temporary. New TMS techniques, which may improve clinical utility, are being developed to enhance clinical utilities in various neurological diseases
URI

http://ir.ymlib.yonsei.ac.kr/handle/22282913/93738
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Neurology
Yonsei Authors
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