Korean Journal of Gastrointestinal Endoscopy (대한소화기내시경학회지), Vol.42(3) : 143~151, 2011
Korean Journal of Gastrointestinal Endoscopy (대한소화기내시경학회지)
Background/Aims: Eosinophilic esophagitis (EoE) has emerged as one of the most
common causes of dysphagia and esophageal food impactions. However, it is
doubtful that gastroenterologists and pathologists make the correct diagnosis of EoE
because of the insufficient recognition of EoE based on the endoscopic and
pathological findings. This study was performed to investigate the symptoms and
the endoscopic and pathologic findings of EoE as compared with those of
nonobstructive dysphagia (NOD).
Methods: We retrospectively reviewed the medical records and the endoscopic
and pathologic findings from 12 patients who were diagnosed with EoE based on
an eosinophil count of ≥20 per high-power field (HPF) and 13 patients diagnosed
with NOD, and these patients were treated at our hospital from June 2006 till
Results: The endoscopic findings of EoE included rings (41.7%), furrows (75.0%),
exudates (33.3%), mucosal friability (8.3%) and multi-findings (6.7%). Furrows and
multi-findings were identified more frequently in EoE as comparison to that in
NOD. The pathologic findings revealed that the maximal eosinophil counts/HPF
were 87.2 (range 20∼232) and 2.2 (0∼11) in EoE and NOD, respectively.
Moreover, eosinophil microabscess (58.3%), degranulation (100%) and spongiosis
(91.7%) were more significantly observed in EoE compared with that in NOD.
Conclusions: EoE had specific endoscopic and clinicopathologic features that
distinguish it from NOD. For patients with dysphagia, the endoscopic and
pathologic findings of EoE should be kept in mind