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The effect of ephedrine on intraoperative hypothermia.

Title
 The effect of ephedrine on intraoperative hypothermia.
Authors
 Youn Yi Jo; Ji Young Kim; Cheung Soo Shin; Youngjun Kwon; Joon-Sik Kim
Issue Date
2011
Journal Title
 Korean Journal of Anesthesiology
ISSN
 2005-6419
Citation
 Korean Journal of Anesthesiology, Vol.60(4) : 250~254, 2011
Abstract
BACKGROUND: Prevention of intraoperative hypothermia has become a standard of operative care. Since ephedrine has a thermogenic effect and it is frequently used to treat hypotension during anesthesia, this study was designed to determine the effect of ephedrine on intraoperative hypothermia of patients who are undergoing spine surgery. METHODS: Twenty-four patients were randomly divided to receive an ephedrine (the ephedrine group, n = 12) or normal saline (the control group, n = 12) infusion for 2 h. The esophageal temperature (the core temperature), the index finger temperature (the peripheral temperature) and the hemodynamic variables such as the mean blood pressure and heart rate were measured every 15 minutes after the intubation. RESULTS: At the end of the study period, the esophageal temperature and hemodynamic variables were significantly decreased in the control group, whereas those in the ephedrine group were stably maintained. The index finger temperature was significantly lower in the ephedrine group compared to that in the control group, suggesting the prevention of core-to-peripheral redistribution of the heat as the cause of temperature maintenance. CONCLUSIONS: An intraoperative infusion of ephedrine minimized the decrease of the core temperature and it stably maintained the hemodynamic variables during spine surgery with the patient under general anesthesia.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/93643
DOI
10.4097/kjae.2011.60.4.250
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Anesthesiology and Pain Medicine
Yonsei Authors
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