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A scoring system for prediction of lateral neck node metastasis from papillary thyroid cancer

Title
A scoring system for prediction of lateral neck node metastasis from papillary thyroid cancer
Authors
Jong Ju Jeong;Yong Sang Lee;Cheong Soo Park;Ki Jun Song;Won Youl Seo;Hang-Seok Chang;Woong Youn Chung;Sang-Wook Kang;Seung Chul Lee
Issue Date
2011
Journal Title
Journal of Korean Medical Science
ISSN
1011-8934
Citation
Journal of Korean Medical Science, Vol.26(8) : 996~1000, 2011
Abstract
Lateral neck node metastasis is an important prognostic factor in thyroid carcinoma. We developed a scoring system for use in prediction of lateral neck node metastasis from papillary thyroid cancer. In this study, 161 consecutive patients were included in the training data set. This scoring system, named the Yonsei Estimated Value (YEV) for lymph node metastasis in papillary thyroid cancer, was developed on the basis of results from multivariate logistic regression analysis of preoperative clinical and radiologic data. Sixty eight consecutive patients were included for testing of the validity of the scoring system. The equation for prediction of lateral neck node metastasis was follows:YEV (Yonsei Estimated Value) = 1/(1+X)X = Exp (5.333-[0.902 × sex]+[0.036 × age]-[1.020 × tumor size]-[0.177 × lymph node size]-[0.032 × lymph node density])When the YEV was 0.3 or more, the probability of lateral neck node metastasis was 79.0%, with sensitivity of 76.3%, specificity of 69.8%, positive predictive value of 56.7%, and negative predictive value of 85.1% in the training set. When fine needle aspiration biopsy for suspicious lateral neck nodes is not possible, or the results are inadequate, our scoring system for prediction of lateral neck node metastasis can be helpful in optimization of the surgical extent for each patient.
URI

http://ir.ymlib.yonsei.ac.kr/handle/22282913/93628
DOI
10.3346/jkms.2011.26.8.996
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Surgery
1. 연구논문 > 1. College of Medicine > Dept. of Biostatistics
Yonsei Authors
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