Brain Tumor Research and Treatment (대한뇌종양학회지), Vol.10(2) : 138-141, 2011
Brain Tumor Research and Treatment (대한뇌종양학회지)
Objective: Multicentric glioblastoma is an uncommon condition, about 2.3 to 9% of all glioblastoma. There have been few reports about the prognosis of multicentric glioblastoma after multimodal treatment. We describe our experience of one case of multicentric glioblastoma.
Case: A 50-year-old male patient presented to the neurosurgery clinic with complex partial seizure attack and partial conduction aphasia. A brain magnetic resonance image (MRI) scan showed two enhanced lesions on left temporal and occipital lobes and one on right frontal lobe. Left temporal lesion was partially resected and the pathologic diagnosis was glioblastoma. Right frontal lesion was also removed totally and it was glioblastoma. Concomitant hemoradiation therapy (CCRT) with Temodal was started. At the time of 6th cycle, right hemiparesis developed and the follow-up MRI revealed progression of left temporal region. And he expired 54 weeks after diagnosis.
Conclusion: We experienced a patient of synchronous multicentric and multifocal glioblastoma who showed 12 months of survival period after CCRT with tumor resection.