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Dysplastic Odontogenic Cyst with the Manifestation of Inflammatory Radicular Cyst

Title
Dysplastic Odontogenic Cyst with the Manifestation of Inflammatory Radicular Cyst
Other Titles
염증성 치근단낭종의 소견을 보이는 이형성 치성낭종
Authors
Takashi Muramatsu;유미현;Masaki Shimono;김진;이상휘;Sadamitsu Hashimoto
Issue Date
2011
Journal Title
Korean Journal of Oral and Maxillofacial Pathology (대한구강악안면병리학회지)
ISSN
1225-1577
Citation
Korean Journal of Oral and Maxillofacial Pathology (대한구강악안면병리학회지), Vol.35(3) : 195~199, 2011
Abstract
This report describes a case of odontogenic cyst with keratinization and dysplastic change of lining epithelium, which showed the manifestation of inflammatory radicular cyst, clinically. A 28-year-old man complained of dull pain in the right mandibular molar region. Radiographically a well-defined oval cystic lesion with non-vital teeth, a common finding in radicular cyst, was observed. Microscopically, the lining epithelium of the cyst demonstrated both keratinization and severe epithelial dysplasia. Atypical findings such as hyperchromatic nuclei, increase of N/C ratio and drop shaped rege ridge were observed in the lining epithelium. However, definite invasion into fibrous connective tissue was not found. Immunohistochemically, the dysplastic lining epithelium was highly positive for proliferative marker, Ki-67. Based on the dysplastic changes of lining epithelium, this periapical lesion would be considered to be signs of malignant change. From this case, we conclude that definitive diagnosis by microscopical examination should be made, even if the periapical lesion would be clinically considered as inflammatory radicular cyst
URI
http://www.dbpia.co.kr/Article/1655081

http://ir.ymlib.yonsei.ac.kr/handle/22282913/93360
Appears in Collections:
1. 연구논문 > 2. College of Dentistry > Dept. of Oral and Maxillofacial Surgery
1. 연구논문 > 2. College of Dentistry > Dept. of Oral Pathology
Yonsei Authors
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