Journal of Multiple Sclerosis (대한다발성경화증학회지), Vol.2(1) : 16~19, 2011
Journal of Multiple Sclerosis (대한다발성경화증학회지)
NMO-IgG is highly specific for neuromyelitis optica and reacts with the water channel aquaporin 4,
which expressed particularly in the periventricular and periaqueductal areas, including dorsomedial
regions of the medulla oblongata, where emetic circuitry may exist. We report an intractable vomiting
in a NMO-IgG positive patient. She suffered from recurrent myelitis. Brain MRI revealed a single
focal T2 high signal intensity in the area postrema or nucleus tractus solitaries. Intractable vomiting
may be caused by neuromyelitis optica spectrum disorder.