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Comparison of laparoscopic versus open radical nephrectomy for large renal tumors: a retrospective analysis of multi-center results.

Title
 Comparison of laparoscopic versus open radical nephrectomy for large renal tumors: a retrospective analysis of multi-center results. 
Authors
 Seung Hyun Jeon ; Tae Gyun Kwon ; Seok-Soo Byun ; Hyeon Hoe Kim ; Sung Hoo Hong ; Young Beom Jeong ; Jae Sung Lim ; Wan Lee ; Gyung Tak Sung ; Koon Ho Rha 
Issue Date
2011
Journal Title
 BJU International 
ISSN
 1464-4096 
Citation
 BJU International, Vol.107(5) : 817~821, 2011 
Abstract
OBJECTIVE: • To assess the feasibility and oncologic efficacy of laparoscopic radical nephrectomy (LRN) compared with open radical nephrectomy (ORN) in patients with large renal cell carcinomas (RCCs) > 7 cm in size. PATIENTS AND METHODS: • We analysed the data from 255 patients who underwent radical nephrectomies at 26 institutions in Korea between January 2000 and December 2007 for RCCs > 7 cm in size. • Eighty-eight patients who underwent LRNs were compared with 167 patients who underwent ORNs. The patients with tumor thrombi in the renal vein or IVC, and lymph node or distant metastases were excluded. • We compared the operative time, estimated blood loss, complication rates, and 2-year overall and disease-free survival rates between the LRN and ORN groups. RESULTS: • The median duration of postoperative follow-up was 19 months for the LRN group and 25.8 months for the ORN group. • The operative time was significantly longer in the LRN group than in the ORN group (241.5 ± 74.8 min vs 202.7 ± 69.6 min, P < 0.001) and blood loss was significantly lower in the LRN group than in the ORN group (439.8 ± 326.8 mL vs 604.4 ± 531.4 mL, P = 0.006). • No statistically significant difference was found in complication rates, the 2-year overall (92.7% vs 94%, P = 0.586) and disease-specific (90.1% vs 93.7%, P = 0.314) survival rates between the LRN and ORN groups. CONCLUSIONS: • Despite the longer operative time, LRN was an effective
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/93251
DOI
10.1111/j.1464-410X.2010.09688.x
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Urology
Yonsei Authors
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Link
 http://onlinelibrary.wiley.com/doi/10.1111/j.1464-410X.2010.09688.x/abstract;jsessionid=AB5E855AD927AFA7E09B43B2D0FC973C.f04t03
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