Interspecies dissemination of the bla gene encoding PER-1 extended-spectrum β-lactamase
Il Kwon Bae ; Sook Jin Jang ; Kyungwon Lee ; Byungkyu Cho ; Seok Hoon Jeong ; Juwon Kim
Antimicrobial Agents and Chemotherapy, Vol.55(3) : 1305~1307, 2011
Antimicrobial Agents and Chemotherapy
PER-1 extended-spectrum β-lactamase-producing Gram-negative bacilli are resistant to oxyimino-cephalosporins. However, the bla(PER-1) gene has never been reported in Klebsiella pneumoniae. Here, we studied interspecies dissemination of the bla(PER-1) gene by horizontal transfer of Tn1213 among Acinetobacter baumannii, Pseudomonas aeruginosa, and K. pneumoniae. In a K. pneumoniae clinical isolate, the bla(PER-1) gene was located on a 150-kbp incompatibility group A/C plasmid.