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조현병 및 조현정동장애 입원환자에서 혈청 염증표지자와 정신병적증상과의 관련성
DC Field | Value | Language |
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dc.contributor.author | 박진영 | - |
dc.date.accessioned | 2014-12-19T17:59:07Z | - |
dc.date.available | 2014-12-19T17:59:07Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 1225-8709 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/92432 | - |
dc.description.abstract | Objectives : Despite the growing research interest in the role of immunological markers in schizophrenia, a few studies, with conflicting results, have focused on the association between high sensitivity C-reactive protein (hs-CRP) levels and clinical characteristics in schizophrenia. The aim of the present study was to examine the association of serum hs-CRP with psychopathology in schizophrenia. Methods : Fifty-five inpatients with schizophrenia or schizoaffective disorder were enrolled. Serum levels of hs-CRP were measured, and each patient was assessed with the Korean version of the Positive and Negative Syndrome Scale (PANSS). Results : In correlation analysis of hs-CRP with PANSS subscales, positive subscale score has significant positive correlation (r = 0.271, p = 0.046). In independent t-test analysis, subjects with hs-CRP > 0.3 mg/dL (elevated CRP group, n = 43) had significantly higher PANSS positive subscale score (t = -3.273, df = 24.107, p = 0.003) than those with hs-CRP ≤ 0.3 mg/dL (normal CRP group, n = 12). Conclusions : Elevated serum levels of high sensitivity C-reactive protein in schizophrenia are associated with the severity of psychotic symptoms. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 193~198 | - |
dc.relation.isPartOf | Korean Journal of Biological Psychiatry (생물정신의학) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 조현병 및 조현정동장애 입원환자에서 혈청 염증표지자와 정신병적증상과의 관련성 | - |
dc.title.alternative | Relationship between Serum Inflammatory Marker and Psychotic Symptoms in Inpatients with Schizophrenia or Schizoaffective Disorder | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Psychiatry (정신과학) | - |
dc.contributor.googleauthor | 김계환 | - |
dc.contributor.googleauthor | 이건석 | - |
dc.contributor.googleauthor | 김수진 | - |
dc.contributor.googleauthor | 이은규 | - |
dc.contributor.googleauthor | 송열매 | - |
dc.contributor.googleauthor | 박진영 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01701 | - |
dc.relation.journalcode | J01967 | - |
dc.identifier.pmid | C-reactive protein ; Inflammatory marker ; Schizophrenia ; Positive symptoms | - |
dc.subject.keyword | C-reactive protein | - |
dc.subject.keyword | Inflammatory marker | - |
dc.subject.keyword | Schizophrenia | - |
dc.subject.keyword | Positive symptoms | - |
dc.contributor.alternativeName | Park, Jin Young | - |
dc.contributor.affiliatedAuthor | Park, Jin Young | - |
dc.citation.volume | 19 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 193 | - |
dc.citation.endPage | 198 | - |
dc.identifier.bibliographicCitation | Korean Journal of Biological Psychiatry (생물정신의학), Vol.19(4) : 193-198, 2012 | - |
dc.identifier.rimsid | 29503 | - |
dc.type.rims | ART | - |
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