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유방 병변의 감별에서 탄성초음파와 회색조 초음파의 진단 성적 비교

Title
 유방 병변의 감별에서 탄성초음파와 회색조 초음파의 진단 성적 비교 
Other Titles
 Comparison of Diagnostic Performance of US Elastography and Conventional B-mode US in Differentiation of Breast Lesions 
Authors
 강지영 ; 이진화 ; 최순섭 ; 박병호 ; 하동호 ; 조진한 ; 김병권 ; 신수영 ; 김은경 
Issue Date
2012
Journal Title
 대한초음파의학회지 
ISSN
 1015-7085 
Citation
 대한초음파의학회지, Vol.31(4) : 239~245, 2012 
Abstract
Purpose: The purpose of this study was to compare the diagnostic performance of ultrasound (US) elastography and conventional B-mode US for discrimination between benign and malignant breast lesions. Materials and Methods: During a 13-month period, 277 women with 335 sonographically visible breast lesions who were scheduled to undergo biopsy were examined with US elastography. Elastographic findings were classified as benign or malignant based on the area ratio, with 1.00 as the threshold. Findings on conventional Bmode US were classified according to the BI-RADS category, as follows: lesions of BIRADS categories 2 and 3 were considered benign, while those in categories 4 and 5 were considered malignant. Statistical analysis included sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, and ROC curve analysis for comparison of the diagnostic performance of US elastography and conventional B-mode US. Results: Of the 335 breast lesions, 85 (25.4%) showed malignancy on pathology. Findings on B-mode US showed malignancy in 264 (78.8%) and elastographic findings showed malignancy in 102 (30.4%). The sensitivity, specificity, PPV, NPV, and accuracy of B-mode US and elastography were 98.8%, 28.0%, 31.8%, 98.6%, and 79.4% and 69.4%, 81.2%, 57.8%, 88.8%, and 79.4%, respectively. Elastography showed significantly higher specificity and PPV and lower sensitivity and NPV, compared with B-mode US (p < 0.001). The area under the ROC curve (AUC value) was 0.761 for elastography, and 0.634 for B-mode US (p < 0.001). Conclusions: US elastography can improve specificity and PPV of B-mode US, but with significant sacrifice of sensitivity and NPV. Therefore, US elastography may complement B-mode US for differentiation of breast masses.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/92376
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
Yonsei Authors
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