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Curved biodegradable microneedles for vascular drug delivery

Title
Curved biodegradable microneedles for vascular drug delivery
Authors
Chang Kuk Choi;Jin Bum Kim;Won Hyoung Ryu;Young-Nam Youn;Eui Hwa Jang
Issue Date
2012
Journal Title
Small
ISSN
1613-6810
Citation
Small, Vol.8(16) : 2483~2488, 2012
Abstract
Curved biodegradable microneedles for application to the outer surface of blood vessels are produced to enhance drug delivery to vascular tissues suffering from hyperplasia or atherosclerosis. Spatially discrete thermal drawing and post-annealing processes are employed to fabricate microneedles on a curved surface. Insertion of microneedles into arteries in vivo and ex vivo is demonstrated, and their mechanical properties and drug-delivery function are studied
URI
http://onlinelibrary.wiley.com/doi/10.1002/smll.201200441/abstract

http://ir.ymlib.yonsei.ac.kr/handle/22282913/91856
DOI
10.1002/smll.201200441
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Thoracic & Cardiovascular Surgery
Yonsei Authors
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