A Case of Intractable Bisphosphonate-Related Osteonecrosis of the Jaw Treated with Teriparatide
유전자 재조합 인간 부갑상선호르몬(1-34)으로 회복된 비스포스포네이트 연관 악골 괴사 증례
이수진 ; 허지혜 ; 이유미 ; 차인호 ; 김경민 ; 김원진
Osteoporosis, Vol.10(2) : 76~81, 2012
Bisphosphonates are the most widely used medications for treating high bone turnover osteoporosis, Paget's disease of bone, multiple myeloma and metastatic carcinomas, etc. However, a destructive complication of bisphosphonate-related osteonecrosis of the jaw (BRONJ) can occur. The treatments of BRONJ are challenging and the currently recommended managements for BRONJ are still controversial. Our case demonstrated that teriparatide can be a treatment of choice for intractable BRONJ, which had not been cured for 2 years even with the proper surgical treatment and withdrawal of bisphosphonates.