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Clinical outcomes and prognostic factors for surgically resected second primary lung cancer

Title
 Clinical outcomes and prognostic factors for surgically resected second primary lung cancer
Authors
 Mi Kyung Bae; Chun Sung Byun; Kyung Young Chung; Dae Joon Kim; In Kyu Park; Jin Gu Lee; Chang Young Lee
Issue Date
2012
Journal Title
 Journal of Thoracic and Cardiovascular Surgery
ISSN
 0022-5223
Citation
 Journal of Thoracic and Cardiovascular Surgery, Vol.60(8) : 525~532, 2012
Abstract
BACKGROUND: This study was designed to analyze the predictive factors for survival in second primary lung cancer patients following operation. METHODS: A total of 1852 patients who underwent resection for primary lung cancer between January 1990 and December 2008 were reviewed, retrospectively. RESULTS: Nineteen patients were treated for synchronous second primary lung cancer and 23 patients were treated for metachronous cancer. The overall 5-year survival rate for patients with synchronous second primary lung cancer was comparable to that of patients with single-lung cancer (51.4 vs. 48.7%, p = 0.755). The overall 5-year survival rate after the first tumor resection in patients with metachronous second primary lung cancer was significantly better than that of patients with single-lung cancer (85.4 vs. 48.7%, p = 0.003), but was not significantly different after the second tumor resection (77.0 vs. 48.7%, p = 0.057). CONCLUSION: Surgically resected second primary lung cancer had a survival comparable with single-lung cancer. Histologic concordance between the first and second tumors, and the pathological stage were important prognostic factors in second primary lung cancer.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/91172
DOI
10.1055/s-0031-1293603
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Thoracic & Cardiovascular Surgery
Yonsei Authors
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Link
 https://www.thieme-connect.com/DOI/DOI?10.1055/s-0031-1293603
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