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Clinical factors associated with hepatitis A virus seropositivity in HIV-infected adults living in a country with an epidemiologic shift for hepatitis A virus infection

Title
Clinical factors associated with hepatitis A virus seropositivity in HIV-infected adults living in a country with an epidemiologic shift for hepatitis A virus infection
Authors
Ji Hyeon Baek;Chang Oh Kim;June Myung Kim;Young Goo Song;Jun Yong Choi;Sang Hoon Han;Hye Won Kim;Nam Soo Koo;Su Jin Jeong;Jun Yong Park
Issue Date
2012
Journal Title
Journal of Korean Medical Science
ISSN
1011-8934
Citation
Journal of Korean Medical Science, Vol.27(8) : 969~971, 2012
Abstract
The number of HIV-infected individuals susceptible to Hepatitis A virus (HAV) infection is increasing in Korea; however, it has proven difficult to devise a vaccination policy therefore because limited seroepidemiologic data exists for them. Accordingly, anti-HAV IgG was measured in 188 HIV-infected adults between July 2008 and July 2010. The nadir CD4+ T lymphocyte counts were not different between the HAV-positive and -negative groups (197 ± 138 vs 202 ± 129, P = 0.821). The only factor independently associated with seropositive status was age under 40 yr old (OR 0.017, P < 0.001). Our findings suggest that HAV vaccination in HIV-infected adults should be targeted at persons under the age of 40 yr.
URI

http://ir.ymlib.yonsei.ac.kr/handle/22282913/90901
DOI
10.3346/jkms.2012.27.8.969
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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