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Personalized medicine in breast cancer: a systematic review

Title
Personalized medicine in breast cancer: a systematic review
Authors
Sang-Hoon Cho;Jongsu Jeon;Seung Il Kim
Issue Date
2012
Journal Title
Journal of Breast Cancer
ISSN
1738-6756
Citation
Journal of Breast Cancer, Vol.15(3) : 265~272, 2012
Abstract
The recent advent of "-omics" technologies have heralded a new era of personalized medicine. Personalized medicine is referred to as the ability to segment heterogeneous subsets of patients whose response to a therapeutic intervention within each subset is homogeneous. This new paradigm in healthcare is beginning to affect both research and clinical practice. The key to success in personalized medicine is to uncover molecular biomarkers that drive individual variability in clinical outcomes or drug responses. In this review, we begin with an overview of personalized medicine in breast cancer and illustrate the most encountered statistical approaches in the recent literature tailored for uncovering gene signatures.
URI

http://ir.ymlib.yonsei.ac.kr/handle/22282913/90644
DOI
10.4048/jbc.2012.15.3.265
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Surgery
Yonsei Authors
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