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Antimicrobial Resistance of Neisseria gonorrhoeae Isolated in Korea

Title
Antimicrobial Resistance of Neisseria gonorrhoeae Isolated in Korea
Authors
Lee H;Lee K;Chong Y
Issue Date
2012
Journal Title
Journal of Bacteriology and Virology
ISSN
1598-2467
Citation
Journal of Bacteriology and Virology, Vol.42(1) : 9~16, 2012
Abstract
Neisseria gonorrhoeae is the causative agent of gonorrhea, one of the most important sexually transmitted diseases. The incidence of gonorrhea is still prevalent and about 50,000 new cases have been reported annually during the late 2000s in Korea. The antimicrobial resistance of N. gonorrhoeae is very prevalent and most isolates are multi-drug resistant to penicillin G, tetracycline, and fluoroquinolones. The incidence of penicillinase-producing N. gonorrhoeae (PPNG) decreased significantly, but high-level tetracycline-resistant N. gonorrhoeae (TRNG) increased recently. The minimum inhibitory concentrations (MICs) of ceftriaxone were within the susceptible range for all isolates, but MIC creep has been apparent and one cefixime-nonsusceptible isolate (0.5 µg/ml) was found. Spectinomycin-resistant isolates remain rare, but caution should be required when dealing with gonococcal pharyngitis.
URI

http://ir.ymlib.yonsei.ac.kr/handle/22282913/90623
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Laboratory Medicine
Yonsei Authors
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