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Chronic obstructive pulmonary disease and metabolic syndrome: a nationwide survey in Korea.

Title
Chronic obstructive pulmonary disease and metabolic syndrome: a nationwide survey in Korea.
Authors
B. H. Park;M. S. Park;C. Kim;Y. S. Kim;J. Y. Jung;Y. A. Kang;S. K. Kim;J. Chang
Issue Date
2012
Journal Title
International Journal of Tuberculosis and Lung Disease
ISSN
1027-3719
Citation
International Journal of Tuberculosis and Lung Disease, Vol.16(5) : 694~700, 2012
Abstract
SETTING: Systemic inflammation has been suggested to be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD) and metabolic syndrome. However, the association between these two conditions is not fully understood. OBJECTIVE: To evaluate the relationship between COPD and metabolic syndrome. DESIGN: Among subjects aged ≥40 years from the 2001 Korean National Health and Nutrition Examination Survey, 1215 subjects with two or more acceptable spirometry measurements and complete anthropometric/laboratory examinations were analysed. RESULTS: A total of 133 subjects (11%, 100 men and 33 women) were newly diagnosed with COPD (forced expiratory volume in 1 second/forced vital capacity ≤ 70%). The prevalence of metabolic syndrome, based on the National Cholesterol Education Program Adult Treatment Panel III, was significantly higher in COPD subjects compared with non-COPD subjects in both sexes (33.0% vs. 22.2% in men and 48.5% vs. 29.6% in women). In men, the risk of COPD was higher in subjects with metabolic syndrome than in those without (OR 2.03, 95%CI 1.08-3.80), after adjusting for potential confounders. There was a borderline significant association between COPD and abdominal obesity among the individual component of metabolic syndrome (OR 1.95, 95%CI 0.93-4.11). CONCLUSION: In the Republic of Korea, metabolic syndrome was associated with COPD in men.
URI
http://www.ingentaconnect.com/content/iuatld/ijtld/2012/00000016/00000005/art00026

http://ir.ymlib.yonsei.ac.kr/handle/22282913/90553
DOI
10.5588/ijtld.11.0180
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
1. 연구논문 > 1. College of Medicine > Dept. of Preventive Medicine
Yonsei Authors
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