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Protein kinases as targets for interventive biogerontology: Overview and perspectives

Title
Protein kinases as targets for interventive biogerontology: Overview and perspectives
Authors
Wing-Fu Lai
Issue Date
2012
Journal Title
Experimental Gerontology
ISSN
0531-5565
Citation
Experimental Gerontology, Vol.47(4) : 290~294, 2012
Abstract
Protein kinases are enzymes that catalyze the transfer of γ phosphate from adenosine triphosphate to substrate proteins, and are important signal transduction mediators in a diversity of biological processes, ranging from apoptosis to energy metabolism. In this article, we will take this prominent class of proteins as an example to illustrate the involvement of proteins in modulation of aging and to highlight the prospects and challenges of protein-targeted interventions for anti-aging purposes. It is hoped that through this article, more empirical work on interventive gerontology will follow, and with collaborative endeavors among researchers, hurdles in anti-aging intervention development can be overcome in the near future.
URI
http://www.sciencedirect.com/science/article/pii/S0531556512000150

http://ir.ymlib.yonsei.ac.kr/handle/22282913/90281
DOI
10.1016/j.exger.2012.01.002
Appears in Collections:
1. 연구논문 > 2. College of Dentistry > Dept. of Oral Biology
Yonsei Authors
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