Cited 7 times in

Incidence and 30-day mortality of peptic ulcer bleeding in Korea.

Title
 Incidence and 30-day mortality of peptic ulcer bleeding in Korea.
Authors
 Bae, Seung Jin; Kim, Nayoung; Shim, Ki-Nam; Jung, Sung Woo; Kim, Jie-Hyun; Cho, Yu Kyung; Kim, Kyoung-Min; Kim, Dong-Sook; Kang, Jung Mook
Issue Date
2012
Journal Title
 European Journal of Gastroenterology & Hepatology
ISSN
 0954-691X
Citation
 European Journal of Gastroenterology & Hepatology, Vol.24(6) : 675~682, 2012
Abstract
OBJECTIVES: To estimate the rates of peptic ulcer bleeding (PUB) incidence and the association of demographic factors with 30-day mortality after PUB. METHODS: Diagnostic algorithms for PUB were derived and validated on the basis of 115 true PUB patients at one tertiary hospital in 2005, followed by estimation of age-specific PUB incidence and 30-day mortality rates, using the Korean National Health Insurance claim database. A Cox proportional hazard model was used to determine the impact of demographic factors on the 30-day mortality rate ratio (MRR) after PUB. RESULTS: The diagnostic algorithm showed 89 and 88% positive predictive value and sensitivity, respectively. On the basis of this algorithm, the rate of PUB incidence was 22.1 per 100 000 during 2006-2007 and the age-specific incidence rate increased with advanced age. This incidence rate was more than three times higher among men than women. Among 21 107 PUB patients, the overall 30-day mortality rate was 2.15%, but it ranged from 0.83% for patients younger than 60 years to 7.65% for patients older than 80 years. The adjusted 30-day mortality rate ratio for patients older than 80 was 8.13 (95% confidence interval 6.10-10.8) compared with those younger than 60 and 7.09 (95% confidence interval 2.78-4.51) for patients with a high level of comorbidity compared with a low level of comorbidity. CONCLUSION: PUB incidence was higher among men and increased with advanced age. Increased 30-day mortality was observed in association with increasing age, after adjusting for comorbidity.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/90198
DOI
10.1097/MEG.0b013e3283525a56
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
사서에게 알리기
  feedback
Link
 http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00042737-201206000-00010&LSLINK=80&D=ovft
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse