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Atypical teratoid/rhabdoid tumor: analysis of cytomorphologic features in CSF, focused on the differential diagnosis from mimickers.

Title
 Atypical teratoid/rhabdoid tumor: analysis of cytomorphologic features in CSF, focused on the differential diagnosis from mimickers.
Authors
 Junjeong Choi; Hoguen Kim; Se Hoon Kim
Issue Date
2012
Journal Title
 Diagnostic Cytopathology
ISSN
 8755-1039
Citation
 Diagnostic Cytopathology, Vol.40(7) : 592~596, 2012
Abstract
Atypical teratoid and rhabdoid tumor (AT/RT) is a rare tumor with fatal clinical consequences, usually affecting young children. A significant portion of patients present with dissemination to cerebrobspinal fluid (CSF). However, a limited number of studies are available regarding the cytomorphologic findings of AT/RT in CSF. We collected eight cases of CSF cytology of AT/RT and describe the cytomorphologic features of AT/RT in CSF. Typical rhabdoid cells are found in most cases and they are characterized by eccentric nuclei, abundant cytoplasm, and clustering of the tumor cells. The presence of these cells in CSF indicates disseminated diseases and aggressive therapeutic consideration for patient management is required.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/90127
DOI
10.1002/dc.21594.
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Pathology
Yonsei Authors
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Link
 http://onlinelibrary.wiley.com/doi/10.1002/dc.21594/abstract
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