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Investigation of critical shear stress with simultaneous measurement of electrical impedance, capacitance and light backscattering.

Title
 Investigation of critical shear stress with simultaneous measurement of electrical impedance, capacitance and light backscattering. 
Authors
 Byoung-Kwon Lee ; Jae-yong Ko ; Sehyun Shin ; Jeong-Hun Nam ; Hyun-jung Lim 
Issue Date
2012
Journal Title
 Clinical Hemorheology and MICROCirculation 
ISSN
 1386-0291 
Citation
 Clinical Hemorheology and MICROCirculation, Vol.51(3) : 203~212, 2012 
Abstract
Recent electrical investigation of hemorheology provided useful information on the kinetics of red blood cell (RBC) aggregation. However, because of the inconsistent results in the electrical measurements, we need to understand the electrical characteristics of RBC aggregation at various flow conditions. In the present study, AC electrical-capacitance (EC) and -impedance (EI) and light backscattering (LB) were simultaneously measured for transient shear-decreasing blood flow in a microchannel. EI, EC and LB signals of RBCs in plasma show similar time-varying curves, both yielding either a peak or a minimal point in the optimal frequency range (10~500 kHz). Critical shear stress (CSS) determined from EC showed the nearly same results as that determined from LB, with yielding hematocrits-independence and dextran-concentration dependence. However, the high concentration of fibrinogen caused electrical saturation, which resulted in different results of CSS determined from between LB and EC. These results suggest that electrical properties of RBC suspensions should be further examined to replace the optical method of measurement of RBC aggregation
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/90026
DOI
10.3233/CH-2011-1526
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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Link
 http://iospress.metapress.com/content/12u874507243243n/?genre=article&issn=1386-0291&volume=51&issue=3&spage=203
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