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Comparison of the antitussive effect of remifentanil during recovery from propofol and sevoflurane anaesthesia

Title
Comparison of the antitussive effect of remifentanil during recovery from propofol and sevoflurane anaesthesia
Authors
H. Kim;S.-H. Choi;J.-R. Lee;N.-O. Kim;J.-H. Lee;Y.-S. Choi
Issue Date
2012
Journal Title
Anaesthesia
ISSN
0003-2409
Citation
Anaesthesia, Vol.67(7) : 765~770, 2012
Abstract
This prospective randomised study compared the antitussive effect of remifentanil during recovery from either propofol or sevoflurane anaesthesia. Seventy-four female patients undergoing thyroidectomy were anaesthetised with either propofol and remifentanil or sevoflurane and remifentanil. During recovery, remifentanil was maintained at an effect-site concentration of 2 ng.ml(-1) until extubation and the occurrence of coughing, haemodynamic parameters and recovery profiles were compared between the two groups. During recovery, neither the incidence nor the severity of cough (incidence 20% with propofol; 24% with sevoflurane, p = 0.77), nor the haemodynamic parameters were different between the two groups. Time to awakening and time to extubation were significantly shorter in the propofol group (4.7 min, 6.1 min min, respectively) compared with the sevoflurane group (7.9 min and 8.9 min respectively) (p < 0.001 and p = 0.002, respectively). An effect-site concentration of 2 ng.ml(-1) of remifentanil was associated with smooth emergence from both propofol and sevoflurane anaesthesia.
URI
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2044.2012.07136.x/pdf

http://ir.ymlib.yonsei.ac.kr/handle/22282913/89465
DOI
10.1111/j.1365-2044.2012.07136.x
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Anesthesiology and Pain Medicine
Yonsei Authors
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