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Clinical Implications for Graft Function of a New Equation Model for the Ratio of Living Donor Kidney Volume to Recipient Body Surface Area

Title
 Clinical Implications for Graft Function of a New Equation Model for the Ratio of Living Donor Kidney Volume to Recipient Body Surface Area 
Authors
 Chang Ki Lee ; Young Eun Yoon ; Woong Kyu Han ; Yu Seun Kim ; Kyu Ha Huh ; Dong Jin Joo ; Joong Shik Lee ; Seung Choul Yang ; Kyung Hwa Choi 
Issue Date
2013
Journal Title
 Korean Journal of Urology 
ISSN
 2005-6737 
Citation
 Korean Journal of Urology, Vol.54(12) : 870~875, 2013 
Abstract
PURPOSE: We propose an equation that predicts graft function after kidney transplantation by using donated kidney volume and recipient body surface area (BSA). MATERIALS AND METHODS: Included were 261 cases of living kidney transplantation between 2007 and 2009. Preoperative computed tomography scans were performed and the donated kidney volume was measured by use of a three-dimensional reconstruction program (Ripidia). The estimated glomerular filtration rate (eGFR) was calculated by using the modification of diet in renal disease formula. Donated kidney volume, preoperative renal function, and demographic factors of both donors and recipients were evaluated as predictors. RESULTS: The mean ages of the donors and recipients were 40.8 and 41.6 years, respectively. The mean donated kidney volume and donated kidney volume/recipient BSA ratio were 153.4 mL and 96.9 mL/m(2), respectively. Mean preoperative and postoperative 12-month eGFR of recipients were 7.1 and 59.7 mL/min, respectively, and the mean preoperative eGFR of donors was 92.2 mL/min. Donated kidney volume/recipient BSA ratio, donor age, and recipient gender were the significant predictors of eGFR level (p<0.001) and eGFR<45 mL/min at postoperative 12 months (p=0.005, p<0.001, and p=0.006). From the multiple linear regression equation and predicted probability from logistic regression, we could calculate the equation for the ratio of living donor kidney volume to recipient BSA on graft function. CONCLUSIONS: Graft kidney volume/recipient BSA ratio, donor age, and recipient gender were predictors of graft function 12 months after kidney transplantation. Although we are concerned only with the preoperative, this equation model could help physicians to counsel patients concerning their postoperative prognosis and to avoid insufficient volume donations.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/88684
DOI
10.4111/kju.2013.54.12.870
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Urology
1. 연구논문 > 1. College of Medicine > Dept. of Surgery
Yonsei Authors
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