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A patient-specific model of virtual ablation for atrial fibrillation

Title
 A patient-specific model of virtual ablation for atrial fibrillation
Authors
 Soon-Sung Kwon; Yong Hyun Yun; Eun Bo Shim; Hui-Nam Pak; Seung-Bae Hong
Issue Date
2013
Journal Title
 Conference Proceedings : Engineering in Medicine and Biology Society (EMBC)
ISSN
 1557-170X
Citation
 Conference Proceedings : Engineering in Medicine and Biology Society (EMBC), Vol.2013 : 1522~1525, 2013
Abstract
The purpose of this study was to propose a patient-specific model of atrial fibrillation (AF) and apply it to virtual radiofrequency ablation (RFA). We obtained patient-specific geometries of the left atrium (LA) from CT data and constructed three-dimensional (3D) simulation models. A bidomain Courtemanche model was used to simulate the 3D electric waves on the LA surface, and an S1-S2 protocol was applied to induce AF in the model. To identify scar areas in the models, we converted clinically measured voltage data on the LA surface to the scar maps of the simulation model. Then, after initiation of AF, we applied the virtual ablation scheme to the model and investigated whether the AF was terminated by the scheme. The computed results of AF and ablation were similar to those of clinical observation, providing a clinically important simulation method for preclinical virtual trials of AF treatment.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/88475
DOI
10.1109/EMBC.2013.6609802
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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Link
 http://ieeexplore.ieee.org/xpl/abstractAuthors.jsp?arnumber=6609802
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