Cited 29 times in
Advances in our understanding of the pathogenesis of Henoch-Schönlein purpura and the implications for improving its diagnosis
DC Field | Value | Language |
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dc.contributor.author | 박세진 | - |
dc.contributor.author | 신재일 | - |
dc.date.accessioned | 2014-12-18T09:32:51Z | - |
dc.date.available | 2014-12-18T09:32:51Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1744-666X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/88373 | - |
dc.description.abstract | Henoch-Schönlein purpura (HSP) is a leukocytoclastic vasculitis classically characterized by palpable purpura, arthritis, abdominal pain and renal disease. In this article, we summarize our current understanding of the pathogenesis of HSP and the implications for improving its diagnosis. Although the pathogenesis of HSP is not fully understood yet, exciting new information has emerged in recent years, leading to a better understanding of its pathogenesis. Here, we discuss genetic predisposition, immunoglobulins with a particular emphasis on IgA1, activated complements, cytokines and chemokines, abnormal coagulation and autoantibodies in the underlying pathogenic mechanisms. Finally, diagnostic criteria for HSP developed by institutions such as the American College of Rheumatology and the European League against Rheumatism/Paediatric Rheumatology European Society were proposed to improve early detection and diagnosis. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | EXPERT REVIEW OF CLINICAL IMMUNOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Autoantibodies/immunology* | - |
dc.subject.MESH | Blood Coagulation | - |
dc.subject.MESH | Complement Activation | - |
dc.subject.MESH | Cytokines/immunology* | - |
dc.subject.MESH | Europe | - |
dc.subject.MESH | Genetic Predisposition to Disease | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunoglobulin A/genetics | - |
dc.subject.MESH | Immunoglobulin A/immunology* | - |
dc.subject.MESH | Practice Guidelines as Topic | - |
dc.subject.MESH | Purpura, Schoenlein-Henoch/diagnosis* | - |
dc.subject.MESH | Purpura, Schoenlein-Henoch/etiology | - |
dc.subject.MESH | Purpura, Schoenlein-Henoch/immunology | - |
dc.subject.MESH | United States | - |
dc.title | Advances in our understanding of the pathogenesis of Henoch-Schönlein purpura and the implications for improving its diagnosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Se Jin Park | - |
dc.contributor.googleauthor | Jin-Soon Suh | - |
dc.contributor.googleauthor | Jun Ho Lee | - |
dc.contributor.googleauthor | Jung Won Lee | - |
dc.contributor.googleauthor | Seong Heon Kim | - |
dc.contributor.googleauthor | Kyoung Hee Han | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.identifier.doi | 10.1586/1744666X.2013.850028 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01523 | - |
dc.contributor.localId | A02142 | - |
dc.relation.journalcode | J00880 | - |
dc.identifier.eissn | 1744-8409 | - |
dc.identifier.pmid | 24215411 | - |
dc.identifier.url | http://informahealthcare.com/doi/abs/10.1586/1744666X.2013.850028 | - |
dc.subject.keyword | cytokines | - |
dc.subject.keyword | diagnosis | - |
dc.subject.keyword | genetic susceptibility | - |
dc.subject.keyword | Henoch-Schönlein purpura | - |
dc.subject.keyword | immunoglobulins | - |
dc.subject.keyword | pathogenesis | - |
dc.subject.keyword | vasculitis | - |
dc.contributor.alternativeName | Park, Se Jin | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | Park, Se Jin | - |
dc.contributor.affiliatedAuthor | Shin, Jae Il | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 9 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1223 | - |
dc.citation.endPage | 1238 | - |
dc.identifier.bibliographicCitation | EXPERT REVIEW OF CLINICAL IMMUNOLOGY, Vol.9(12) : 1223-1238, 2013 | - |
dc.identifier.rimsid | 32471 | - |
dc.type.rims | ART | - |
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