Fabrication of TiO₂ Nanowires Using Vapor-Liquid-Solid Process for the Osseointegration
Young-Sik Yun ; Eun-Hye Kang ; Jong-Souk Yeo ; Yong-Oock Kim ; In-Sik Yun
Journal of the Korean Vacuum Society (한국진공학회지), Vol.22(4) : 204~210, 2013
Journal of the Korean Vacuum Society (한국진공학회지)
In order to improve osseointegration for biomedical implants, it is crucial to understand the interactions between nanostructured surfaces and cells. In this study, TiO₂ nanowires were prepared via Vapor-Liquid-Solid (VLS) process with Sn as a metal catalyst in the tube furnace. Nanowires were grown with N₂ heat treatment with their size controlled by the agglomeration of Sn layers in various thicknesses. MC3T3-E1 (pre-osteoblast) were cultured on the TiO₂ nanowires for a week. Preliminary results of the cell culture showed that the cells adhere well on the TiO₂ nanowires.