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ANCA 음성인 전신성 베게너육아종증 1예

Other Titles
 A Case of ANCA-Negative Generalized Wegener's Granulomatosis 
Authors
 김승규 ; 권용진 ; 변민광 ; 김기현 ; 고희성 ; 하지윤 ; 이광원 ; 박혜성 
Citation
 Yeungnam University Journal of Medicine (영남의대학술지), Vol.30(1) : 17~20, 2013 
Journal Title
 Yeungnam University Journal of Medicine (영남의대학술지) 
ISSN
 1225-7737 
Issue Date
2013
Abstract
Wegener's granulomatosis is a very rare systemic vasculitis characterized by necrotizing granulomatosis. The detection of antineutrophil cytoplasm antibody (ANCA) is a valuable finding in diagnosing Wegener's granulomatosis because ANCA is positive in approximately 90 percent of patients with active, generalized Wegener's granulomatosis. But ANCA is not necessarily positive to make a diagnosis. A 59-year-old man was transferred to our hospital. He was diagnosed with lung abscess and treated with antibiotics at previous hospital. Initially, the ANCA was negative in immunofluorescence assay but we suspected Wegener's granulomatosis because of systemic inflammatory symptoms. Clinical symptoms deteriorated rapidly so we did bronchoscopic biopsy early. Wegener's granulomatosis was diagnosed according to pathologic finding that reported necrotizing granulomatous inflammation associated with vasculitis. Thus we treated with steroid then clinical symptoms and laboratory findings were improved.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/87986
DOI
10.12701/yujm.2013.30.1.17
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
1. 연구논문 > 1. College of Medicine > Dept. of Pathology
Yonsei Authors
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