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Successful Graft Recovery from Thrombotic Acute Kidney Injury i n a Kidney Transplant Patient with Antiphospholipid Syndrome

Title
Successful Graft Recovery from Thrombotic Acute Kidney Injury i n a Kidney Transplant Patient with Antiphospholipid Syndrome
Authors
Younjeong Choi;Hyewon Lee;Beom Seok Kim;Hyeonjoo Jeong;Eudong Hwang;Youngki Lee;Yujung Yun
Issue Date
2013
Journal Title
Journal of the Korean Society for Transplantation (대한이식학회지)
ISSN
1598-1711
Citation
Journal of the Korean Society for Transplantation (대한이식학회지), Vol.27(3) : 128~131, 2013
Abstract
Antiphospholipid syndrome nephropathy (APSN) is well documented in the literature as the renal involvement of the antiphospholipid syndrome (APS). A review of literature also shows that among antiphospholipid antibodies, lupus anticoagulant (LA) positivity is recognized as the strongest risk factor for APSN. In addition, APSN is also known to be associated with a poor functional outcome in the first posttransplant year. Therefore, it is a general belief that renal transplantation may be life threatening in APS patients. Furthermore, the presence of LA at the time of transplantation is particularly associated with a high rate of allograft APSN and the consequent poor transplantation outcomes. Here, we report the case that thrombotic acute kidney injury due to APSN after kidney transplantation can be successfully treated if anticoagulation therapy is timely applied with a prompt diagnosis.
URI

http://ir.ymlib.yonsei.ac.kr/handle/22282913/87928
DOI
10.4285/jkstn.2013.27.3.128
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Pathology
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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