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낭성 섬유증이 없었던 환자에서 폐이식 후 발생한 Burkholderia cepacia 폐렴

Other Titles
 A Case of Burkholderia cepacia Pneumonia after Lung Transplantation in a Recipient without Cystic Fibrosis 
Authors
 조진선 ; 나성원 ; 백효채 ; 고신옥 ; 이 반 ; 소 윤 ; 박무석 
Citation
 Korean Journal of Critical Care Medicine (대한중환자의학회지), Vol.28(3) : 187~191, 2013 
Journal Title
 Korean Journal of Critical Care Medicine (대한중환자의학회지) 
ISSN
 1229-4802 
Issue Date
2013
Abstract
Burkholderia cepacia is a highly virulent pathogen known to cause opportunistic infections in immunocompromised patients. It accelerates lung disease and causes necrotizing pneumonia with associated severe sepsis, known as cepacia syndrome. In particular, lung transplant recipients infected with Burkholderia cepacia show higher mortality after lung transplantation than those who are not infected with this organism. Due to broad-spectrum antibiotic resistance, a combination therapy should be used according to the results of the susceptibility test. This bacterial infection is rare in Korea, and no case was reported in lung transplant recipients. However, we report a case of pneumonia caused by Burkholderia cepacia after lung transplantation. As Burkholderia cepacia was grown from a sputum culture, the patient was treated initially with a combination of meropenem and trimethoprim/sulfamethoxazole and then ceftazidime and trimethoprim/sulfamethoxazole as a result of leukopenia. After antibiotics treatment for 20 days, sputum cultures became negative for Burkholderia cepacia and the patient successfully recovered.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/87859
DOI
10.4266/kjccm.2013.28.3.187
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Thoracic & Cardiovascular Surgery
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
1. 연구논문 > 1. College of Medicine > Dept. of Anesthesiology and Pain Medicine
Yonsei Authors
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