Efficient isolation and accurate in situ analysis of circulating tumor cells using detachable beads and a high-pore-density filter
Authors
Hun Joo Lee ; Jin Ho Oh ; Jin Mi Oh ; Jong-Myeon Park ; Jeong-Gun Lee ; Minseok S. Kim ; Yeon Jeong Kim ; Hyun Ju Kang ; Joon Jeong ; Seung Il Kim ; Soo Suk Lee ; Jeong-Woo Choi ; Nam Huh
cancer ; cell capture ; circulating tumor cells ; in situ analysis ; photolysis
Abstract
Analysis of cancer cells: A new technique isolates rare circulating tumor cells (CTCs) and analyzes their protein expression by the use of detachable beads and high-pore-density filters. This technique shows significantly improved efficiency in the isolation of rare CTCs from peripheral blood and enables accurate measurement of in situ protein-expression levels.