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Measurement depth enhancement in terahertz imaging of biological tissues

Title
 Measurement depth enhancement in terahertz imaging of biological tissues
Authors
 Seung Jae Oh; Sang-Hoon Kim; Jin-Suck Suh; Joo-Hiuk Son; Yong-Min Huh; Yeonji Park; Kiyoung Jeong
Issue Date
2013
Journal Title
 Optics Express
ISSN
 1094-4087
Citation
 Optics Express, Vol.21(18) : 21299~21305, 2013
Abstract
We demonstrate the use of a THz penetration-enhancing agent (THz-PEA) to enhance the terahertz (THz) wave penetration depth in tissues. The THz-PEA is a biocompatible material having absorption lower than that of water, and it is easily absorbed into tissues. When using glycerol as a THz-PEA, the peak value of the THz signal which was transmitted through the fresh tissue and reflected by a metal target, was almost doubled compared to that of tissue without glycerol. THz time-of-flight imaging (B-scan) was used to display the sequential glycerol delivery images. Enhancement of the penetration depth was confirmed after an artificial tumor was located below fresh skin. We thus concluded that the THz-PEA technique can potentially be employed to enhance the image contrast of the abnormal lesions below the skin.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/87664
DOI
10.1364/OE.21.021299
Appears in Collections:
1. 연구논문 > 5. Research Institutes > Institute for Medical Convergence
1. 연구논문 > 1. College of Medicine > Yonsei Biomedical Research Center
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
Yonsei Authors
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Link
 http://www.opticsinfobase.org/oe/abstract.cfm?uri=oe-21-18-21299
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