Takayasu arteritis associated with ulcerative colitis and optic neuritis: First case in Korea

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Authors: Jung Yoon Pyo ; Jin Su Park ; Chang Ho Song ; Sang Won Lee ; Yong Beom Park ; Soo Kon Lee

MeSH: Adult ; Anti-Inflammatory Agents/therapeutic use ; Aortography/methods ; Colitis, Ulcerative/complications* ; Colitis, Ulcerative/diagnosis ; Colitis, Ulcerative/drug therapy ; Colonoscopy ; Female ; Humans ; Immunosuppressive Agents/therapeutic use ; Optic Neuritis/complications* ; Optic Neuritis/diagnosis ; Optic Neuritis/drug therapy ; Positron-Emission Tomography ; Republic of Korea ; Steroids/therapeutic use ; Takayasu Arteritis/complications* ; Takayasu Arteritis/diagnosis ; Takayasu Arteritis/drug therapy ; Tomography, X-Ray Computed ; Treatment Outcome

Abstract: Takayasu arteritis (TA) is a chronic vasculitis that affects the aortic arch and its primary branches. Ulcerative colitis (UC) is an inflammatory bowel disease of unknown etiology. Patients diagnosed with both TA and UC have rarely been reported. The pathogenesis of TA and UC is uncertain, but cell-mediated mechanisms play an important role in both diseases, and a genetic factor is thought to have an effect on the coincidence of these two diseases. We herein report a 38-year-old female with TA who had a history of UC with optic neuritis. We believe that this is the first case of the coexistence of TA and UC in Korea.