IgG4-Related Sclerosing Disease Involving the Superior Vena Cava and the Atrial Septum of the Heart
Changho Song ; Myoung Ju Koh ; Se Hoon Kim ; Boyoung Joung ; Yong-Nam Yoon
Yonsei Medical Journal, Vol.54(5) : 1285~1288, 2013
Yonsei Medical Journal
A 55-year-old woman presented with frequent episodes of syncope due to sinus pauses. During ambulatory Holter monitoring, atrial fibrillation and first-degree atrioventricular nodal block were observed. Magnetic resonance imaging and CT scans showed a tumor-like mass from the superior vena cava to the right atrial septum. Open chest cardiac biopsy was performed. The tumor was composed of proliferating IgG4-positive plasma cells and lymphocytes with surrounding sclerosis. The patient was diagnosed with IgG4-related sclerosing disease. Because of frequent sinus pauses and syncope, a permanent pacemaker was implanted. The cardiac mass was inoperable, but it did not progress during the one-year follow-up.