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소아에서 human metapneumovirus 감염의 임상 특징

Title
 소아에서 human metapneumovirus 감염의 임상 특징 
Other Titles
 Clinical Manifestation of Human Metapneumovirus Infection in Korean Children 
Authors
 안정민 ; 최성열 ; 김기환 ; 김동수 
Issue Date
2013
Journal Title
 Korean Journal of Pediatric Infectious Diseases (소아감염) 
ISSN
 1226-3923 
Citation
 Korean Journal of Pediatric Infectious Diseases (소아감염), Vol.20(1) : 28~35, 2013 
Abstract
Purpose : The aim of this study was to determine the frequency, epidemiology and the clinical manifestation of human metapneumovirus (hMPV) infection in Korean children. Methods : From February 2010 to January 2012, we collected nasopharyngeal aspiration from 1,554 children who were hospitalized for acute lower respiratory tract infections at the Department of Pediatrics, Severance Children’s Hospital. hMPV was detected by performing reverse transcriptase-polymerase chain reaction (RT-PCR). The medical records of the patients with positive results were retrospectively reviewed. Results : We detected hMPV in 99 of the 1,554 hospitalized children. The mean age of the hMPV infected children was 25 months, and 87% of the illnesses occurred between April and June. The most common diagnoses were pneumonia (73%) and bronchiolitis (16%). The clinical manifestations included cough, fever, respiratory distress, hoarseness, tachypnea, and wheezing. Coinfection with other respiratory viruses was found in 43 children (43%). Conclusion : hMPV is one of the major virus causing acute respiratory tract infection in the age between 13 months and 48 months old with peaks during April to June. Reports of hMPV in Korea has been increasing but additional studies are required to define the epidemiology and the extent of disease caused by hMPV to determine future development of this illness in Korean children.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/87385
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Pediatrics
Yonsei Authors
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