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Different Perfusion Pattern Between Acute and Chronic Pulmonary Thromboembolism: Evaluation With Two-Phase Dual-Energy Perfusion CT Read More: http://www.ajronline.org/doi/abs/10.2214/AJR.12.8697

Title
Different Perfusion Pattern Between Acute and Chronic Pulmonary Thromboembolism: Evaluation With Two-Phase Dual-Energy Perfusion CT Read More: http://www.ajronline.org/doi/abs/10.2214/AJR.12.8697
Authors
Yoo Jin Hong;Ja Young Kim;Young Jin Kim;Byoung Wook Choi;Hye-Jeong Lee;Jin Hur;Kyu Ok Choe
Issue Date
2013
Journal Title
American Journal of Roentgenology
ISSN
0361-803X
Citation
American Journal of Roentgenology, Vol.200(4) : 812~817, 2013
Abstract
OBJECTIVE: The purpose of this study was to evaluate whether two-phase dual-energy CT can differentiate between lung perfusion patterns of patients with chronic pulmonary thromboembolism (PTE) and those of patients with acute PTE. SUBJECTS AND METHODS: A total of 114 patients clinically suspected to have PTE were prospectively enrolled. All patients underwent dual-energy CT at pulmonary artery (PA) and delayed phases. Of 68 patients diagnosed with PTE on CT, 42 were finally included. Iodine-related attenuation values (IRAs) were measured in PA and delayed phases for each lung segment, and IRA change ratios were calculated using the formula 100% × [(IRA of delayed phase) - (IRA of PA phase)]/(IRA of PA phase). RESULTS: Among the 42 patients (19 men and 23 women; mean age, 60.3 ± 13.2 years; range, 28-82 years), 24 had a diagnosis of acute PTE and 18 of chronic PTE. Those segments with both perfusion and filling defects (n = 143) in patients with acute PTE showed no significant changes of mean IRA between PA and delayed phases, whereas the segments from patients with chronic PTE (n = 94) showed significantly increased IRA on delayed phase as compared with PA phase. The mean IRA change ratios in acute and chronic PTE were -3.14% and 191.9%, respectively (p < 0.0001). CONCLUSION: Chronic PTE segments were significantly more enhanced on the delayed phase of two-phase dual-energy CT images than were acute PTE segments, possibly resulting from more extensive systemic collateral formation in chronic PTE. Two-phase dual-energy CT can be used to differentiate distinct regional perfusion patterns between acute and chronic PTE.
URI
http://www.ajronline.org/doi/abs/10.2214/AJR.12.8697

http://ir.ymlib.yonsei.ac.kr/handle/22282913/87077
DOI
10.2214/AJR.12.8697
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
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