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Pleiotropic Functions of Fibroblast Growth Factor Signaling in Embryonic Mammary Gland Development

Authors
 김은정 ; 정한성 
Citation
 Journal of Mammary Gland Biology and Neoplasia, Vol.18(2) : 139~142, 2013 
Journal Title
 Journal of Mammary Gland Biology and Neoplasia 
ISSN
 1083-3021 
Issue Date
2013
Abstract
The mammary gland is an ectodermal appendage and a defining feature of mammals. Consistent with it being a recent evolutionary novelty, many of the molecules essential for the ontogeny and morphogenesis of various vertebrate organs, including those in the fibroblast growth factor (FGF) signaling pathway, are co-opted for induction, maintenance and morphogenesis of the mammary glands. Understanding the mechanism whereby FGF signaling regulates the fundamental cell behavior during normal mammary gland develop may facilitate determination of the consequences of its deregulation during breast cancer progression.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/87002
DOI
10.1007/s10911-013-9278-4
Appears in Collections:
1. 연구논문 > 2. College of Dentistry > Dept. of Oral Biology
Yonsei Authors
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Link
 http://link.springer.com/article/10.1007%2Fs10911-013-9278-4
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