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Pleiotropic Functions of Fibroblast Growth Factor Signaling in Embryonic Mammary Gland Development

Title
Pleiotropic Functions of Fibroblast Growth Factor Signaling in Embryonic Mammary Gland Development
Authors
Eun-Jung Kim;Han-Sung Jung;Pengfei Lu
Issue Date
2013
Journal Title
Journal of Mammary Gland Biology and Neoplasia
ISSN
1083-3021
Citation
Journal of Mammary Gland Biology and Neoplasia, Vol.18(2) : 139~142, 2013
Abstract
The mammary gland is an ectodermal appendage and a defining feature of mammals. Consistent with it being a recent evolutionary novelty, many of the molecules essential for the ontogeny and morphogenesis of various vertebrate organs, including those in the fibroblast growth factor (FGF) signaling pathway, are co-opted for induction, maintenance and morphogenesis of the mammary glands. Understanding the mechanism whereby FGF signaling regulates the fundamental cell behavior during normal mammary gland develop may facilitate determination of the consequences of its deregulation during breast cancer progression.
URI
http://link.springer.com/article/10.1007%2Fs10911-013-9278-4

http://ir.ymlib.yonsei.ac.kr/handle/22282913/87002
DOI
10.1007/s10911-013-9278-4
Appears in Collections:
1. 연구논문 > 2. College of Dentistry > Dept. of Oral Biology
Yonsei Authors
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