A Case of Immunoglobulin E Mediated Anaphylaxis to Levodropropizine
Kyung Hee Park ; Il Seon Yun ; Jung-Won Park ; Chein-Soo Hong ; Jae-Hyun Lee ; Soo-Young Choi
Yonsei Medical Journal, Vol.54(1) : 262~264, 2013
Yonsei Medical Journal
We experienced a case of immunoglobulin E (IgE) mediated anaphylaxis to levodropropizine. The patient was an 18-year old Korean woman. After taking the common cold medication including acetaminophen, domperidone, and levodropropizine, skin rash, angioedema and anaphylaxis were developed immediately. As she was tolerable to acetaminophen alone, we thought the culprit agent was maybe a levodropropizine tablet. To confirm the culprit, she underwent skin prick test and oral drug provocation test with the suspected one. Finally we detected levodropropizine specific IgE and confirmed the specificity by inhibition enzyme-linked immunosorbent assay (ELISA).