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Arterial ageing

Authors
 박성하 
Citation
 Korean Circulation Journal (순환기), Vol.43(2) : 73~79, 2013 
Journal Title
 Korean Circulation Journal (순환기) 
ISSN
 1738-5520 
Issue Date
2013
Abstract
Arterial ageing is characterized by age associated degeneration and sclerosis of the media layer of the large arteries. However, besides ageing, clinical conditions, which enhance oxidative stress and inflammation act to accelerate the degree of arterial ageing. In this review, we summarized the pathophysiology and contributing factors that accelerate arterial ageing. Among them, we focused on hypertension, the renin-angiotensin-aldosterone system and vascular inflammation which are modifiable causes of the arterial ageing process. Also, novel treatment targets derived from the disease models such as the Hutchinson Gilford Progeria Syndrome were reviewed.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/86533
DOI
10.4070/kcj.2013.43.2.73
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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