CTX-M-55-Type Extended-Spectrum β-lactamase-Producing Shigella sonnei Isolated from a Korean Patient Who Had Travelled to China
Wonmok Lee ; Hae-Sun Chung ; Yunsop Chong ; Kyungwon Lee ; Seok Hoon Jeong ; Dongeun Yong ; Jong Hwa Yum ; Hyukmin Lee
Annals of Laboratory Medicine, Vol.33(2) : 141~144, 2013
Annals of Laboratory Medicine
We report a case of CTX-M-55-type extended-spectrum β-lactamase (ESBL)-producing Shigella sonnei infection in a 27-year-old Korean woman who had traveled to China. The patient was admitted to the hospital due to abdominal pain, watery diarrhea, and fever (39.3℃). S. sonnei was isolated from her stool specimens, and the pathogen was found to be resistant to cefotaxime due to CTX-M-55-type ESBL. Insertion sequence (IS)Ecp1 was found upstream of the blaCTX-M-55 gene. The blaCTX-M-55 gene was transferred from the S. sonnei isolate to an Escherichia coli J53 recipient by conjugation. Pulsed-field gel electrophoresis and Southern blotting revealed that the blaCTX-M-55 gene was located on a plasmid of approximately 130 kb.