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Association of Prophylactic Distal Perfusion Cannulation With Mortality in Patients Receiving Venoarterial Extracorporeal Membrane Oxygenation
DC Field | Value | Language |
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dc.contributor.author | 안철민 | - |
dc.contributor.author | 이혁희 | - |
dc.contributor.author | 이승준 | - |
dc.contributor.author | 홍성진 | - |
dc.contributor.author | 김중선 | - |
dc.contributor.author | 김현창 | - |
dc.contributor.author | 김병극 | - |
dc.contributor.author | 고영국 | - |
dc.contributor.author | 최동훈 | - |
dc.contributor.author | 홍명기 | - |
dc.date.accessioned | 2024-03-22T05:45:52Z | - |
dc.date.available | 2024-03-22T05:45:52Z | - |
dc.date.issued | 2023-11 | - |
dc.identifier.issn | 0002-9149 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/198191 | - |
dc.description.abstract | Prophylactic distal perfusion cannulation (PDPC) is protectively associated with limb ischemia in patients with cardiogenic shock (CS) receiving femoral venoarterial extracorporeal membrane oxygenation (VA-ECMO). However, evidence supporting its benefits beyond limb ischemia reduction is scarce. We aimed to investigate whether PDPC, compared with no-PDPC, is associated with a lower risk of mortality in patients receiving VA-ECMO. From a multicenter registry, we identified 479 patients who underwent VA-ECMO support for refractory CS. The association of PDPC with 30-day mortality was assessed using multiple methods, including instrumental variable analysis, overlap weighting, and propensity score matching. Of the 479 patients, 154 (32.2%) received PDPC. The 30-day mortality rate was 33.1% in the PDPC group and 53.2% in the no-PDPC group. The instrumental variable analysis showed a protective association of PDPC with 30-day mortality (absolute risk difference −16.7%, 95% confidence interval −31.3% to −2.1%; relative risk 0.68, 95% confidence interval 0.40 to 0.96). The findings were consistent in the overlap-weighted analysis (hazard ratio 0.68, 95% confidence interval 0.48 to 0.98) and in the propensity score–matched analysis (hazard ratio 0.67, 95% confidence interval 0.45 to 1.00). There were no significant differences in safety outcomes, including stroke, ECMO site bleeding, gastrointestinal bleeding, and sepsis, between PDPC and no-PDPC. In conclusion, PDPC was associated with a lower risk of mortality at 30 days in patients with CS receiving VA-ECMO. The efficacy and safety of PDPC merit evaluation in future randomized studies. Clinical trial registration: ClinicalTrials.gov; NCT02985008. © 2023 Elsevier Inc. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Excerpta Medica | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Catheterization | - |
dc.subject.MESH | Extracorporeal Membrane Oxygenation* / methods | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Ischemia / etiology | - |
dc.subject.MESH | Ischemia / prevention & control | - |
dc.subject.MESH | Perfusion | - |
dc.subject.MESH | Peripheral Vascular Diseases* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Shock, Cardiogenic / etiology | - |
dc.title | Association of Prophylactic Distal Perfusion Cannulation With Mortality in Patients Receiving Venoarterial Extracorporeal Membrane Oxygenation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Hyeok-Hee Lee | - |
dc.contributor.googleauthor | Woo Jin Jang | - |
dc.contributor.googleauthor | Chul-Min Ahn | - |
dc.contributor.googleauthor | Woo Jung Chun | - |
dc.contributor.googleauthor | Ju Hyeon Oh | - |
dc.contributor.googleauthor | Yong Hwan Park | - |
dc.contributor.googleauthor | Seung-Jun Lee | - |
dc.contributor.googleauthor | Sung-Jin Hong | - |
dc.contributor.googleauthor | Jeong Hoon Yang | - |
dc.contributor.googleauthor | Jung-Sun Kim | - |
dc.contributor.googleauthor | Hyeon Chang Kim | - |
dc.contributor.googleauthor | Byeong-Keuk Kim | - |
dc.contributor.googleauthor | Cheol Woong Yu | - |
dc.contributor.googleauthor | Hyun-Joong Kim | - |
dc.contributor.googleauthor | Jang-Whan Bae | - |
dc.contributor.googleauthor | Young-Guk Ko | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Hyeon-Cheol Gwon | - |
dc.contributor.googleauthor | Myeong-Ki Hong | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.identifier.doi | 10.1016/j.amjcard.2023.07.149 | - |
dc.contributor.localId | A02269 | - |
dc.relation.journalcode | J00071 | - |
dc.identifier.eissn | 1879-1913 | - |
dc.identifier.pmid | 37797547 | - |
dc.identifier.url | https://linkinghub.elsevier.com/retrieve/pii/S0002-9149(23)00718-X | - |
dc.subject.keyword | distal perfusion | - |
dc.subject.keyword | extracorporeal membrane oxygenation | - |
dc.subject.keyword | mortality | - |
dc.subject.keyword | prophylaxis | - |
dc.contributor.alternativeName | Ahn, Chul-Min | - |
dc.contributor.affiliatedAuthor | 안철민 | - |
dc.citation.volume | 207 | - |
dc.citation.startPage | 418 | - |
dc.citation.endPage | 425 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF CARDIOLOGY, Vol.207 : 418-425, 2023-11 | - |
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